The Histocompatibility Laboratory (or HLA Lab) was started in 1987 to provide tissue typing and crossmatching for the Kidney Transplant Program at East Texas Medical Center. Organs donors are tissue typed and matched with patients on the kidney transplant waiting list.
All patients waiting for organs are listed with United Network for Organ Sharing (UNOS). Using the computer system provided by UNOS, patient are matched with the donors according to their HLA antigen typing or tissue typing. The final and probably the most important step is the crossmatch between the patients serum and donor lymphocytes. This will determine if there are antibodies in the patients serum that would attach to the donor lymphocytes.
The services the HLA Lab provides are Class I and Class II tissue typing by serology and molecular methods, crossmatching and PRA testing by flow cytometry and serology. The Laboratory is accredited through The American Society for Histocompatibility and Immunogenetics (ASHI).
Please contact Curt Jordan, Assistant Director of HLA, at [email protected] with any questions regarding Histocompatibility or organ transplantation. Phone: (903) 535-5417 Fax: (903) 535-5416
From The United Network for Organ Sharing:
“There is a critical organ shortage: despite continuing advances in medicine and technology, the demand for organs drastically exceeds the number of organ donors…”
Director: Dr. Geoffrey Land, PhD
Assistant Director: Curt Jordan, CHS (ABHI) MT(ASCP)
Technologist: Terry Moore, CHS(ABHI) MT(ASCP)
Technologist: Christie Stephens, BS
The following links can provide information about Organ donation and Histocompatibility.
Southwest Transplant Alliance
United Network for Organ Sharing
American Society of Transplantantion
National Marrow Donor Program
South-Eastern Organ Procurement Foundation
American Society for Histocompatibility and Immunogenetics
“To Provide a safe and sufficient blood supply to the community”
815 South Baxter Avenue, Tyler, Texas 75701
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